A B.C. biotech firm is seeking federal approval for the emergency use of a nasal spray, claiming it significantly lessens the impact and severity of COVID-19 for those who use it. (Pixabay)

A B.C. biotech firm is seeking federal approval for the emergency use of a nasal spray, claiming it significantly lessens the impact and severity of COVID-19 for those who use it. (Pixabay)

B.C. biotech firm seeks emergency approval for COVID-killing nasal spray

Clinical trials found SaNOtize reduces virus levels in upper airways by more than 99%, developers say

A B.C. biotech firm is seeking federal approval for the emergency use of a nasal spray, claiming it significantly lessens the impact and severity of COVID-19 for those who use it.

The Vancouver start-up said clinical trials found SaNOtize reduced coronavirus levels in participants’ upper airways by 95 per cent in one day and more than 99 per cent in three.

The portable treatment expels a nitric oxide solution, “halt(ing) viral replication within the nasal cavity, which rapidly reduces viral load,” said Dr. Chris Miller, chief science officer and co-founder.

“This is significant because viral load has been linked to infectivity and poor outcomes,” Miller said.

During months of testing, COVID-19 patients in Canada and the U.K. self-administered the nasal spray. When treated quickly enough, the virus was eliminated before it spread to the lungs.

SaNOtize also proved effective against COVID-19 variant B117, which originated in the U.K.

READ MORE: B.C. researchers generating COVID-19 breath test that could give results in 1 minute

None of the participants reported adverse side effects during trials.

If approved for use, SaNOtize could help those with COVID-19 experience milder symptoms and potentially recover quicker from the disease, according to Miller.

“We must move with urgency to get it into the hands of the public where it can help bring an end to the pandemic and prevent future outbreaks of COVID-19 and its variants,” said Dr. Gilly Regev, CEO and co-founder.

The developers are hoping the nasal spray can be used internationally, as a form of protection against COVID-19, similar to that of hand sanitizer.

The biotech company is planning clinical trials to prove SaNOtize can prevent COVID-19 transmission in humans. The product is expected to cost $50 per bottle if it makes its way to consumers.

RELATED: Vancouver biotech company discovering antibodies for COVID-19 treatment



sarah.grochowski@bpdigital.ca

Like us on Facebook and follow us on Twitter.

Want to support local journalism? Make a donation here.

CoronavirusHealth

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

CNC’s Applied Research and Innovation had partnered with the Scientific Advisory Committee of the Cariboo Agricultural Research Alliance and Mackin Creek Farm after receiving funding from the Canadian Agricultural Partnership to research a number of solutions potentially extending northern growing seasons. (Photo submitted)
Ways to extend growing season in B.C.’s north explored by College of New Caledonia in Quesnel

Low-cost supplemental LED lighting appears to benefit plant growth

Ecosystem restoration burn planned northwest of Quesnel near Neewa Creek

Burning will take place between April 19 and 30, 2021

Robert Merz recently shared some history behind Merz Road on Facebook. Originally built as a portion of the old Nazko Road, he said Merz Road was named to honour his grandfather and long-time Bouchie Lake resident Walt Merz. (Robert Merz Facebook photo)
Bouchie Lake residents record history with Rural Road Name Challenge

Residents explore and share origins of road names

The City of Quesnel issued an evacuation order for the property 1927 Dragon Hill Road, where the business Marshall Veterinary Hospital is located, due to the risk of landslide Thursday, April 15. (Marshall Veterinary Clinic Facebook photo)
Marshall Veterinary Hospital staff left scrambling after receiving evacuation order

Quesnel business ordered to evacuate due to landslide risk

Rainbow trouts thrashing with life as they’re about to be transferred to the largest lake of their lives, even though it’s pretty small. These rainbows have a blue tinge because they matched the blue of their hatchery pen, but soon they’ll take on the green-browns of their new home at Lookout Lake. (Zoe Ducklow/News Staff)
VIDEO: B.C. lake stocked with hatchery trout to delight of a seniors fishing club

The Cherish Trout Scouts made plans to come back fishing soon

Vancouver Police Const. Deepak Sood is under review by the Independent Investigations Office of B.C. after making comments to a harm reduction advocate Sunday, April 11. (Screen grab)
VIDEO: Vancouver officer convicted of uttering threats under watchdog review again

Const. Deepak Sood was recorded Sunday saying ‘I’ll smack you’ and ‘go back to selling drugs’ to a harm reduction advocate

Provincial health officer Dr. Bonnie Henry prepares a daily update on the coronavirus pandemic, April 21, 2020. (B.C. Government)
B.C.’s COVID-19 infection rate persists, 1,005 new cases Friday

Hospitalization up to 425, six more virus-related deaths

Premier John Horgan receives a dose of the AstraZeneca COVID-19 vaccine at the pharmacy in James Bay Thrifty’s Foods in Victoria, B.C., on Friday, April 16, 2021. THE CANADIAN PRESS/Chad Hipolito
B.C. Premier John Horgan gets AstraZeneca shot, encourages others

27% of residents in B.C. have now been vaccinated against COVID-19

The Nautical Dog Cafe at Skaha marina is getting its patio ready in hopes Mother Nature will provide where provincial restrictions have taken away indoor dining. (Facebook)
‘A lot of instability’: B.C. restaurants in layoff limbo

As COVID-19 cases stay high, restaurants in British Columbia are closed to indoor dining

Prime Minister Justin Trudeau looks on as Deputy Prime Minister and Finance Minister Chrystia Freeland responds to a question during a news conference on Parliament Hill in Ottawa, Tuesday, Aug. 18, 2020. THE CANADIAN PRESS/Adrian Wyld
Expectations high as Trudeau Liberals get ready to unveil first pandemic budget

The Liberals will look to thread an economic needle with Monday’s budget

Since April 4, 38 flights with COVID-19 cases have departed from Vancouver International Airport, while 23 arrived. (Phil McLachlan/Capital News)
Vancouver the largest source of domestic flights with COVID-19 cases: data

This month alone, 38 flights with COVID-19 cases have departed from Vancouver International Airport, while 23 arrived

John Furlong, Own The Podium board chairman and former CEO of the Vancouver Olympics, addresses a Vancouver Board of Trade luncheon in Vancouver, B.C., on Wednesday November 25, 2015.THE CANADIAN PRESS/Darryl Dyck
John Furlong presents 2030 Winter Games vision to Vancouver Board of Trade

Vancouver and Whistler would remain among host sites because of 2010 sport venues still operational

Photo by Metro Creative Connection
New campgrounds coming to B.C. parks as part of $83M provincial boost

This season alone, 185 campsites are being added to provincial parks, says Minister of Environment and Climate Change

Most Read